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Descriptions are generated automatically from the ICTVdB database including links. Some descriptions are only very basic and links may point to documents that are not yet published on the Web.

03.019.0.01.014.00.044.004. SARS-Coronavirus BJ01

Cite this publication as: Sara Mullins for ICTVdB Management (2005). 03.019.0.01.014.00.044.004. SARS-Coronavirus BJ01. In: ICTVdB - The Universal Virus Database, version 3. Büchen-Osmond, C. (Ed), ICTVdB Management, Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 3. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Isolation Details

Isolate designation: BJ01.
Isolation date: Patient died on the 7th; isolate was derived at autopsy March; 2003.
Location: Shanxi Province; China.
Source of isolate: human.

Virus was isolated by Dr Qingyu Zhu; Institute of Microbiology and Epidemiology; Chinese Academy of Military Medical Sciences; Beijing; 100071; China. Email: qingyzh@yahoo.com.cn. Involved in the submission of the isolate was also Dr. E'de Qin; Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China; Dr. Man Yu; Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China; Dr. Baochang Fan; Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China.

Reference: Qin, E., Zhu, W., Yu, M., et. al. (2003) A Complete Sequence and Comparative Analysis of a SARS-Associated Virus (Isolate BJ01). Chinese Science Bulletin, Vol.

Classification

This is a description of a vertebrate virus at the isolate level.

ICTVdB Virus Code: 03.019.0.01.014.00.044.004. Virus accession number: SARSI003. Former accession number: 40FD660E. NCBI Taxonomy ID: [228407].

Biocontainment Level

Distribution of this virus falls under quarantine restrictions. It is recommended to handle this virus at the biocontainment level BSL-3.

Name, Synonyms and Lineage

Virus is assigned to species 03.019.0.01.014. Severe acute respiratory syndrome coronavirus. Virus is assigned to the genus 03.019.0.01. Coronavirus , family 03.019. Coronaviridae , order 03. Nidovirales.

Depositories and Collections

The isolate has been deposited at the Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China.

Virion Properties

Introduction

Particles contain nucleic acid. { } Nucleic acid of virions is encapsidated.

Virion Properties

Morphology

Virions have a complex construction and consist of an envelope, spikes, and a nucleocapsid. Virus capsid (core) is enveloped.

Nucleic Acid

The genome is not segmented and consists of a single molecule of linear, positive-sense, single-stranded RNA. The complete genome is 29725 nucleotides long. The RNA has been fully sequenced and complete sequence is 29725 nucleotides long; sequence can be accessed at GenBank with the accession number [AY278488]. The 5'-end of the genome has a cap; cap is a methylated nucleotide cap. The 3'-terminus has a poly (A) tract 15 nucleotides in length.

Proteins

The viral genome encodes structural proteins and non-structural proteins.

Biological Properties

Natural Host Range

Viral hosts belong to the Domain Eucarya.

Domain Eucarya Kingdom Animalia.

Kingdom Animalia Phylum Chordata.

Phylum Vertebrata Subphylum Vertebrata.

Class Mammalia.

Class Mammalia Order Primates;
Family Hominidae; virus infects Homo sapiens (human).

Host and isolation details Virus was isolated from an adult. Virus was isolated from autopsy (patient is also the source of isolate BJ03). Virus was isolated from lung tissue.

General Symptoms in Animals Infection can affect the The patient was diagnosed with SARS before he died, but no specific symptoms were given. General symptoms include death.

Contributor

Data have been submitted online to ICTVdB on 01-12-05 by
Sara Mullins
American Type Culture Collection
George Mason University
PW II, 10801 University Boulevard
Manassas, VA 20110
United States of America
Tel: + 703-365-2700.
Fax: + 703-365-2701.
Email: Sara Mullins.

The description has been generated automatically from DELTA files.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References

Last updated:15 March 2005 by Cornelia Büchen-Osmond
Web Page generated from ICTVdB by the DELTA systems.

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